The identification and validation of biomarkers for diagnosing alzheimers disease ad and other forms of dementia are increasingly important to date elisa measurement of amyloid1 42 total tau and phospho tau 181 in cerebrospinal fluid csf is the most advanced and accepted method to . The alzheimers disease biomarkers are neurochemical indicators used to assess the risk or presence of the disease the biomarkers can be used to diagnose alzheimers disease ad in a very early stage but they also provide objective and reliable measures of disease progress. Biomarkers for earlier detection current diagnosis of alzheimers disease relies largely on documenting mental decline at which point alzheimers has already caused severe brain damage researchers hope to discover an easy and accurate way to detect alzheimers before these devastating symptoms begin. Developing new biomarkers is a priority for the alzheimers drug discovery foundation addf these tools are critical to the success of our mission to find effective ways to prevent and treat alzheimers disease and other types of dementia. Biomarkers in alzheimers disease provides a comprehensive overview of all modalities of alzheimers disease biomarkers including neuroimaging cerebrospinal fluid genomic and peripheral systems each chapter integrates molecular cellular abnormality due to alzheimers disease and technological advancement of biomarkers techniques
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